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Trustee Election Ballots Have Been Mailed

Participate in the selection of members who serve on the ASA Board of Trustees by voting online or by paper ballot.  If you are sending in your paper ballot, use the enclosed envelope addressed to The Chairman of the Tellers. Please do not send it to the ASA office. We cannot forward it for you.

Here are the 2020 Trustee candidates. Please take the time to get to know them.

What Does it Mean to be a Carrier, Free, or Affected for Different Genetic Defects?

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Many genetic defects are simple recessive traits, meaning it takes two bad alleles (versions of a gene) to see the condition. If an animal is tested free (for instance DDF means tested free for DD), the animal does not have one of these defective alleles. If the animal is a carrier (DDC) then that animal has one normal copy and one defective copy of the gene. If an animal is affected (DDA) then both copies of the gene are defective. Typically we would expect these affected animals to show the signs (phenotype) for that genetic condition. The only way to get affected animals is to mate a carrier bull to a carrier dam. In carrier to carrier matings, we expect 25% of the progeny to be free, 50% to be carriers and 25% to be affected.

In the case of DD, some animals have both defective copies of the gene but don’t show any sign of the genetic condition (this is called incomplete penetrance). With incomplete penetrance, some other factor is needed for the phenotype to display. This trigger may be environmental (nutritional, stress, etc.) or genetic (a second gene involved in the pathway).

 
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Down to the Genes Series

Focus on Genetic Holds and Defect Testing

October 20, 2019 DNA
by ASA's DNA Department | Genetic defect testing and genetic holds are two of the most common subjects ASA’s DNA department handles. This month’s article will explore the most commonly-asked questions within this subject. When is genetic defect testing required? For all AI sires, herd sires, and donor dams, if risk is present on TraitTrac and not cleared by test or pedigree, the progeny will go…
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